CXCR3 anticorps (Internal Region)

N° du produit ABIN7218090

Cet anticorps anti-CXCR3 est un anticorps Lapin Polyclonal détectant CXCR3 dans WB, ELISA et IHC (p). Adapté pour Humain.

Aperçu rapide pour CXCR3 anticorps (Internal Region) (ABIN7218090)

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CXCR3 anticorps

Épitope: Internal Region

Fonction: CXCR-3 Polyclonal Antibody

Specificité: CXCR-3 Polyclonal Antibody detects endogenous levels of CXCR-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human CXCR-3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CXCR3

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Autre désignation: CXCR-3

Sujet: Rabbit Anti-CXCR-3 Polyclonal Antibody,CXCR3, GPR9, C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, CKR-L2, G protein-coupled receptor 9, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183,CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID: 12782716).,C-X-C chemokine receptor type 3

Poids moléculaire: observerd band 37kDa

ID gène: 2833

UniProt: P49682