CSH1 anticorps (AA 161-210)

N° du produit ABIN7226954

Cet anticorps Lapin Polyclonal détecte spécifiquement CSH1 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CSH1 anticorps (AA 161-210) (ABIN7226954)

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-CSH1 anticorps

Épitope: AA 161-210

Fonction: Rabbit Anti-CSH1 Polyclonal Antibody

Specificité: The antibody detects endogenous CSH1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic peptide from human protein at AA range: 161-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300,WB 1:500-2000,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CSH1

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Autre désignation: CSH1

Sujet: CSH1, CSH2The protein encoded by CSH1 (chorionic somatomammotropin hormone 1) is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. CSH1 is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in CSH1 result in placental lactogen deficiency and Silver-Russell syndrome.

Poids moléculaire: 25kD

ID gène: 1442

UniProt: P01243

Pathways: Response to Growth Hormone Stimulus