CBX5 anticorps (pSer92)
Aperçu rapide pour CBX5 anticorps (pSer92) (ABIN7220722)
Antigène
Voir toutes CBX5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer92
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Fonction
- HP1α (phospho Ser92) Polyclonal Antibody
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Specificité
- Phospho-HP1α (S92) Polyclonal Antibody detects endogenous levels of HP1α protein only when phosphorylated at S92.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human HP1alpha Phospho-Ser92
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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Autre désignation
- HP1alpha
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Sujet
- Rabbit Anti-HP1α (phospho Ser92) Polyclonal Antibody,CBX5, HP1A, Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha,CBX5 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The chromobox 5 is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.,Chromobox protein homolog 5
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ID gène
- 23468
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UniProt
- P45973
Antigène
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