Claudin 1 anticorps

N° du produit ABIN7225808

Cet anticorps anti-Claudin 1 est un anticorps Lapin Polyclonal détectant Claudin 1 dans WB et ELISA. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour Claudin 1 anticorps (ABIN7225808)

Antigène: Claudin 1 (CLDN1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Claudin 1 anticorps

Fonction: Claudin-1 Polyclonal Antibody

Specificité: Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Claudin-1 around the non-phosphorylation site of Y210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Claudin 1

Antigène: Claudin 1 (CLDN1)

Autre désignation: Claudin-1

Sujet: Rabbit Anti-Claudin-1 Polyclonal Antibody,CLDN1, CLD1, SEMP1, Claudin-1, Senescence-associated epithelial membrane protein,Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by CLDN1 (claudin 1), a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.,Claudin-1

Poids moléculaire: observerd band 30kDa

ID gène: 9076

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C