CLDN8 anticorps (AA 50-130)

N° du produit ABIN7225800

Cet anticorps anti-CLDN8 est un anticorps Lapin Polyclonal détectant CLDN8 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour CLDN8 anticorps (AA 50-130) (ABIN7225800)

Antigène: CLDN8 (Claudin 8 (CLDN8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLDN8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CLDN8 anticorps

Épitope: AA 50-130

Fonction: Claudin-8 Polyclonal Antibody

Specificité: Claudin-8 Polyclonal Antibody detects endogenous levels of Claudin-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Claudin-8 at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CLDN8

Antigène: CLDN8 (Claudin 8 (CLDN8))

Autre désignation: Claudin-8

Sujet: Rabbit Anti-Claudin-8 Polyclonal Antibody,CLDN8, Claudin-8,CLDN8 (claudin 8) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of CLDN8 has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.,Claudin-8

Poids moléculaire: observerd band 28kDa

ID gène: 9073

UniProt: P56748

Pathways: Hepatitis C