CIRBP anticorps

N° du produit ABIN7227910

Cet anticorps Lapin Polyclonal détecte spécifiquement CIRBP dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CIRBP anticorps (ABIN7227910)

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIRBP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CIRBP anticorps

Fonction: Rabbit Anti-CIRBP Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CIRBP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CIRBP protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CIRBP

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Autre désignation: CIRBP

Sujet: Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRPCIRBP (Cold Inducible RNA Binding Protein) is a Protein Coding gene. Diseases associated with CIRBP include Cryptorchidism. Among its related pathways are DNA Damage and Translational Control. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Poids moléculaire: 18kD

ID gène: 1153

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization