COX-1 anticorps (AA 520-600)

N° du produit ABIN7214300

L’anticorps anti-COX-1 Polyclonal Lapin est utilisé pour la détection de COX-1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour COX-1 anticorps (AA 520-600) (ABIN7214300)

Antigène: COX-1

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-COX-1 anticorps

Épitope: AA 520-600

Fonction: Rabbit Anti-Cox-1 Polyclonal Antibody

Specificité: Cox-1 Polyclonal Antibody detects endogenous levels of Cox-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Cox-1 at AA range: 520-600

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur COX-1

Antigène: COX-1

Sujet: PTGS1, COX1, Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1PTGS1 is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Prostaglandin-endoperoxide synthase 1 regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein. Prostaglandin-endoperoxide synthase 1 may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 70kD

ID gène: 5742

UniProt: P23219