Cullin 3 anticorps (AA 1-80)

N° du produit ABIN7214382

Cet anticorps Lapin Polyclonal détecte spécifiquement Cullin 3 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Cullin 3 anticorps (AA 1-80) (ABIN7214382)

Antigène: Cullin 3 (CUL3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Cullin 3 anticorps

Épitope: AA 1-80

Fonction: Rabbit Anti-CUL-3 Polyclonal Antibody

Specificité: CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human CUL-3 at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cullin 3

Antigène: Cullin 3 (CUL3)

Autre désignation: CUL-3

Sujet: CUL3, KIAA0617, Cullin-3, CUL-3CUL3 encodes a member of the cullin protein family. Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3.

Poids moléculaire: 90kD

ID gène: 8452

UniProt: Q13618

Pathways: M Phase