Cullin 5 anticorps (AA 560-640)

N° du produit ABIN7228100

Cet anticorps Lapin Polyclonal détecte spécifiquement Cullin 5 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Cullin 5 anticorps (AA 560-640) (ABIN7228100)

Antigène: Cullin 5 (CUL5)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cullin 5 anticorps

Épitope: AA 560-640

Fonction: CUL5 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CUL5 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human CUL5 protein at AA range: 560-640

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Cullin 5

Antigène: Cullin 5 (CUL5)

Autre désignation: CUL5

Sujet: Rabbit Anti-CUL5 Polyclonal Antibody,Cullin-5, CUL-5, Vasopressin-activated calcium-mobilizing receptor 1, VACM-1,Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS (SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.,CUL5

Poids moléculaire: observerd band 85kDa

ID gène: 8065

UniProt: Q93034

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development