CYFIP1 anticorps (AA 980-1060)

N° du produit ABIN7228120

Cet anticorps anti-CYFIP1 Polyclonal Lapin (ABIN7228120) détecte spécifiquement CYFIP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CYFIP1 anticorps (AA 980-1060) (ABIN7228120)

Antigène: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYFIP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CYFIP1 anticorps

Épitope: AA 980-1060

Fonction: Rabbit Anti-CYFP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CYFP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CYFP1 protein at AA range: 980-1060

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CYFIP1

Antigène: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Autre désignation: CYFP1

Sujet: Cytoplasmic FMR1-interacting protein 1 ,Specifically Rac1-associated protein 1, Sra-1CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion. CYFIP1 is a Protein Coding gene. Diseases associated with CYFIP1 include Fragile X Syndrome and Schizophrenia. Among its related pathways are RET signaling and Regulation of actin dynamics for phagocytic cup formation.

Poids moléculaire: 137kD

ID gène: 23191

UniProt: Q7L576