alpha Defensin 1 anticorps (Internal Region)

N° du produit ABIN7220014

Cet anticorps Lapin Polyclonal détecte spécifiquement alpha Defensin 1 dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour alpha Defensin 1 anticorps (Internal Region) (ABIN7220014)

Antigène: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Defensin 1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-alpha Defensin 1 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-Defensin α1 Polyclonal Antibody

Specificité: Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Defensin alpha1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur alpha Defensin 1

Antigène: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Autre désignation: Defensin alpha1

Sujet: DEFA1, DEF1, DEFA2, MRS, DEFA1B, Neutrophil defensin 1, Defensin, alpha 1, HNP-1, HP-1, HP1Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Neutrophil defensin 1 encoded by DEFA1, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Poids moléculaire: 11kD

ID gène: 1667

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin