DEFa3 anticorps (Internal Region)

N° du produit ABIN7220016

L’anticorps anti-DEFa3 Polyclonal Lapin est utilisé pour la détection de DEFa3 dans des échantillons de Humain et Souris. Il a été validé pour IHC, ELISA et IF.

Aperçu rapide pour DEFa3 anticorps (Internal Region) (ABIN7220016)

Antigène: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEFa3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DEFa3 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-Defensin α3 Polyclonal Antibody

Specificité: Defensin α3 Polyclonal Antibody detects endogenous levels of Defensin α3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Defensin alpha3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DEFa3

Antigène: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Autre désignation: Defensin alpha3

Sujet: DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Neutrophil defensin 3 encoded by DEFA3, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. DEFA3 differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.

ID gène: 1668

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin