DENND5A anticorps (AA 650-730)
Aperçu rapide pour DENND5A anticorps (AA 650-730) (ABIN7228184)
Antigène
Voir toutes DENND5A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 650-730
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Fonction
- DEN5A Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of DEN5A protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human DEN5A protein at AA range: 650-730
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DENND5A (DENN/MADD Domain Containing 5A (DENND5A))
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Autre désignation
- DEN5A
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Sujet
- Rabbit Anti-DEN5A Polyclonal Antibody,DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1,DENND5A (DENN Domain Containing 5A) encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in DENND5A are associated with early infantile epileptic encephalopathy-49.,DEN5A
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Poids moléculaire
- observerd band 141kDa
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ID gène
- 23258
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UniProt
- Q6IQ26
Antigène
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