DENND5A anticorps (AA 650-730)

N° du produit ABIN7228184

Cet anticorps Lapin Polyclonal détecte spécifiquement DENND5A dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour DENND5A anticorps (AA 650-730) (ABIN7228184)

Antigène: DENND5A (DENN/MADD Domain Containing 5A (DENND5A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND5A est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-DENND5A anticorps

Épitope: AA 650-730

Fonction: Rabbit Anti-DEN5A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DEN5A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DEN5A protein at AA range: 650-730

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DENND5A

Antigène: DENND5A (DENN/MADD Domain Containing 5A (DENND5A))

Autre désignation: DEN5A

Sujet: DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1DENND5A (DENN Domain Containing 5A) encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in DENND5A are associated with early infantile epileptic encephalopathy-49.

Poids moléculaire: 141kD

ID gène: 23258

UniProt: Q6IQ26