Desmoglein 1 anticorps (AA 130-210)

N° du produit ABIN7220092

L’anticorps Lapin Polyclonal anti-Desmoglein 1 a été validé pour WB et ELISA. Il convient pour détecter Desmoglein 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Desmoglein 1 anticorps (AA 130-210) (ABIN7220092)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmoglein 1 anticorps

Épitope: AA 130-210

Fonction: Dsg1 Polyclonal Antibody

Specificité: Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Dsg1 at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: Dsg1

Sujet: Rabbit Anti-Dsg1 Polyclonal Antibody,DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen,DSG1 encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. DSG1 is found in a cluster with other desmoglein family members on chromosome 18. The desmoglein 1 has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.,Desmoglein-1

Poids moléculaire: observerd band 114kDa

ID gène: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization