Desmoglein 2 anticorps (AA 370-450)
Aperçu rapide pour Desmoglein 2 anticorps (AA 370-450) (ABIN7220094)
Antigène
Voir toutes Desmoglein 2 (DSG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 370-450
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Fonction
- Dsg2 Polyclonal Antibody
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Specificité
- Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Dsg2 at AA range: 370-450
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Desmoglein 2 (DSG2)
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Autre désignation
- Dsg2
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Sujet
- Rabbit Anti-Dsg2 Polyclonal Antibody,DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC,DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.,Desmoglein-2
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Poids moléculaire
- observerd band 140kDa
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ID gène
- 1829
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UniProt
- Q14126
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Pathways
- Cell-Cell Junction Organization
Antigène
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