Desmoglein 3 anticorps

N° du produit ABIN7228308

L’anticorps anti-Desmoglein 3 Polyclonal Lapin est utilisé pour la détection de Desmoglein 3 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Desmoglein 3 anticorps (ABIN7228308)

Antigène: Desmoglein 3 (DSG3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmoglein 3 anticorps

Fonction: Rabbit Anti-DSG3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DSG3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DSG3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Desmoglein 3

Antigène: Desmoglein 3 (DSG3)

Autre désignation: DSG3

Sujet: Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6DSG3 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG3 is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.

Poids moléculaire: 109kD

ID gène: 1830

UniProt: P32926