DPPA4 anticorps

N° du produit ABIN7228284

Cet anticorps anti-DPPA4 Polyclonal Lapin (ABIN7228284) détecte spécifiquement DPPA4 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DPPA4 anticorps (ABIN7228284)

Antigène: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPPA4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DPPA4 anticorps

Fonction: Rabbit Anti-DPPA4 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DPPA4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DPPA4 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DPPA4

Antigène: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Autre désignation: DPPA4

Sujet: Developmental pluripotency-associated protein 4DPPA4 encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18. but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of DPPA4 have been identified. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 33kD

ID gène: 55211

UniProt: Q7L190