Diazepam Binding Inhibitor anticorps (Internal Region)

N° du produit ABIN7213444

L’anticorps anti-Diazepam Binding Inhibitor Polyclonal Lapin est utilisé pour la détection de Diazepam Binding Inhibitor dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Diazepam Binding Inhibitor anticorps (Internal Region) (ABIN7213444)

Antigène: Diazepam Binding Inhibitor (DBI)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Diazepam Binding Inhibitor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Diazepam Binding Inhibitor anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-ACBP Polyclonal Antibody

Specificité: ACBP Polyclonal Antibody detects endogenous levels of ACBP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human ACBP

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Diazepam Binding Inhibitor

Antigène: Diazepam Binding Inhibitor (DBI)

Autre désignation: ACBP

Sujet: DBI, Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EPDBI encodes diazepam binding inhibitor (diazepam binding inhibitor, acyl-CoA binding protein), a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for DBI.

Poids moléculaire: 10kD

ID gène: 1622

UniProt: P07108