AKR1C1 anticorps (AA 30-110)

N° du produit ABIN7219994

L’anticorps anti-AKR1C1 Polyclonal Lapin est utilisé pour la détection de AKR1C1 dans des échantillons de Humain. Il a été validé pour IHC, ELISA et IF.

Aperçu rapide pour AKR1C1 anticorps (AA 30-110) (ABIN7219994)

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-AKR1C1 anticorps

Épitope: AA 30-110

Fonction: Rabbit Anti-DD1 Polyclonal Antibody

Specificité: DD1 Polyclonal Antibody detects endogenous levels of DD1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human DD1 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AKR1C1

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Autre désignation: DD1

Sujet: AKR1C1, DDH, DDH1, Aldo-keto reductase family 1 member C1, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HBAKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Poids moléculaire: 37kD

ID gène: 1645

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process