DMGDH anticorps (AA 790-870)

N° du produit ABIN7214582

L’anticorps anti-DMGDH Polyclonal Lapin est utilisé pour la détection de DMGDH dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour DMGDH anticorps (AA 790-870) (ABIN7214582)

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMGDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-DMGDH anticorps

Épitope: AA 790-870

Fonction: Rabbit Anti-DMGDH Polyclonal Antibody

Specificité: DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human DMGDH at AA range: 790-870

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DMGDH

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Autre désignation: DMGDH

Sujet: DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDHDMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme (dimethylglycine dehydrogenase) is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 97kD

ID gène: 29958

UniProt: Q9UI17