DLG3 anticorps

N° du produit ABIN7228236

Cet anticorps Lapin Polyclonal détecte spécifiquement DLG3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour DLG3 anticorps (ABIN7228236)

Antigène: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DLG3 anticorps

Fonction: Rabbit Anti-DLG3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DLG3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human DLG3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DLG3

Antigène: DLG3 (Discs, Large Homolog 3 (DLG3))

Autre désignation: DLG3

Sujet: Disks large homolog 3, Neuroendocrine-DLG, Synapse-associated protein 102, SAP-102, SAP102DLG3 (Discs Large MAGUK Scaffold Protein 3) is a Protein Coding gene. Diseases associated with DLG3 include X-Linked Non-Specific Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are PI3K-Akt signaling pathway and Protein-protein interactions at synapses. DLG3 encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.

Poids moléculaire: 89kD

ID gène: 1741

UniProt: Q92796