RPA14 anticorps (AA 30-80)

N° du produit ABIN7231134

Cet anticorps anti-RPA14 Polyclonal Lapin (ABIN7231134) détecte spécifiquement RPA14 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RPA14 anticorps (AA 30-80) (ABIN7231134)

Antigène: RPA14 (DNA-directed RNA polymerase I subunit RPA14 (RPA14))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPA14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RPA14 anticorps

Épitope: AA 30-80

Fonction: Rabbit Anti-RPA14 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RPA14

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RPA14 protein at AA range: 30-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RPA14

Antigène: RPA14 (DNA-directed RNA polymerase I subunit RPA14 (RPA14))

Autre désignation: RPA14

Sujet: Replication protein A 14 kDa subunit, RP-A p14, Replication factor A protein 3, RF-A protein 3As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (PubMed: 9430682). In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. RPA3 (Replication Protein A3) is a Protein Coding gene. Diseases associated with RPA3 include Epidemic Typhus and Ovary Serous Adenocarcinoma. Among its related pathways are Mismatch repair and DNA Double-Strand Break Repair.

Poids moléculaire: 14kD

ID gène: 6119

UniProt: P35244