DOK6 anticorps (AA 80-160)

N° du produit ABIN7214610

L’anticorps anti-DOK6 Polyclonal Lapin est utilisé pour la détection de DOK6 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et IHC.

Aperçu rapide pour DOK6 anticorps (AA 80-160) (ABIN7214610)

Antigène: DOK6 (Docking Protein 6 (DOK6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-DOK6 anticorps

Épitope: AA 80-160

Fonction: Rabbit Anti-Dok-6 Polyclonal Antibody

Specificité: Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Dok-6 at AA range: 80-160

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DOK6

Antigène: DOK6 (Docking Protein 6 (DOK6))

Autre désignation: Dok-6

Sujet: DOK6, DOK5L, Docking protein 6, Downstream of tyrosine kinase 6The downstream of kinase family (Dok-1-7) are members of a class of "docking" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

Poids moléculaire: 43kD

ID gène: 220164

UniProt: Q6PKX4