DOK2 anticorps (pTyr299)

N° du produit ABIN7212938

L’anticorps anti-DOK2 Polyclonal Lapin est utilisé pour la détection de DOK2 dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour DOK2 anticorps (pTyr299) (ABIN7212938)

Antigène: DOK2

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-DOK2 anticorps

Épitope: pTyr299

Fonction: Rabbit Anti-Dok-2 (phospho Tyr299) Polyclonal Antibody

Specificité: Phospho-Dok-2 (Y299) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y299.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Dok-2 Phospho-Tyr299

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DOK2

Antigène: DOK2

Autre désignation: Dok-2

Sujet: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)Docking protein 2 encoded by DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 2 binds p120 (RasGAP) from CML cells.

Poids moléculaire: 48kD

ID gène: 9046

UniProt: O60496