DTYMK anticorps (AA 1-80)

N° du produit ABIN7214632

Cet anticorps Lapin Polyclonal détecte spécifiquement DTYMK dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour DTYMK anticorps (AA 1-80) (ABIN7214632)

Antigène: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DTYMK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DTYMK anticorps

Épitope: AA 1-80

Fonction: Rabbit Anti-dTMP Kinase Polyclonal Antibody

Specificité: DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DTYMK

Antigène: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Autre désignation: dTMP Kinase

Sujet: DTYMK, CDC8, TMPK, TYMK, Thymidylate kinase, dTMP kinaseThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Poids moléculaire: 22kD

ID gène: 1841

UniProt: P23919

Pathways: Nucleotide Phosphorylation