dTMP Kinase (AA 1-80) anticorps

N° du produit ABIN7214632

Cet anticorps Lapin Polyclonal détecte spécifiquement dTMP Kinase dans ELISA, WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour dTMP Kinase (AA 1-80) anticorps (ABIN7214632)

Antigène: dTMP Kinase

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 1-80

Fonction: dTMP Kinase Polyclonal Antibody

Specificité: DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détail du antigène

Antigène: dTMP Kinase

Sujet: Rabbit Anti-dTMP Kinase Polyclonal Antibody,DTYMK, CDC8, TMPK, TYMK, Thymidylate kinase, dTMP kinase,Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.,Thymidylate kinase

Poids moléculaire: observerd band 22kDa

ID gène: 1841

UniProt: P23919