DUSP10 anticorps (AA 330-410)
Aperçu rapide pour DUSP10 anticorps (AA 330-410) (ABIN7219282)
Antigène
Voir toutes DUSP10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 330-410
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Fonction
- Rabbit Anti-MKP-5 Polyclonal Antibody
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Specificité
- MKP-5 Polyclonal Antibody detects endogenous levels of MKP-5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the C-terminal region of human MKP-5 at AA range: 330-410
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
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Autre désignation
- MKP-5
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Sujet
- DUSP10, MKP5, Dual specificity protein phosphatase 10, Mitogen-activated protein kinase phosphatase 5, MAP kinase phosphatase 5, MKP-5Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 52kD
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ID gène
- 11221
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UniProt
- Q9Y6W6
Antigène
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