DUSP26 anticorps (AA 130-210)
Aperçu rapide pour DUSP26 anticorps (AA 130-210) (ABIN7228314)
Antigène
Voir toutes DUSP26 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 130-210
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Fonction
- Rabbit Anti-DUS26 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of DUS26 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human DUS26 protein at AA range: 130-210
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
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Autre désignation
- DUS26
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Sujet
- Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3, Low-molecular-mass dual-specificity phosphatase 4, DSP-4, LDP-4, Mitogen-activated protein kinase phosphatase 8, MAP kinase phosphatase 8, MKP-8, Novel amplified gene in thyroid anaplastic cancerDUSP26 encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This Dual Specificity Phosphatase 26 may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 23kD
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ID gène
- 78986
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UniProt
- Q9BV47
Antigène
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