Ectodysplasin A anticorps (Internal Region)

N° du produit ABIN7226662

Cet anticorps anti-Ectodysplasin A Polyclonal Lapin (ABIN7226662) détecte spécifiquement Ectodysplasin A dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Ectodysplasin A anticorps (Internal Region) (ABIN7226662)

Antigène: Ectodysplasin A (EDA)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ectodysplasin A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Ectodysplasin A anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-EDA Polyclonal Antibody

Specificité: EDA Polyclonal Antibody detects endogenous levels of EDA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human EDA

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Ectodysplasin A

Antigène: Ectodysplasin A (EDA)

Autre désignation: EDA

Sujet: EDA, ED1, EDA2, Ectodysplasin-A, Ectodermal dysplasia protein, EDA proteinThe protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for EDA.

Poids moléculaire: 42kD

ID gène: 1896

UniProt: Q92838

Pathways: Tube Formation