EPS15 anticorps (pTyr849)

N° du produit ABIN7220316

Cet anticorps anti-EPS15 Polyclonal Lapin (ABIN7220316) détecte spécifiquement EPS15 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour EPS15 anticorps (pTyr849) (ABIN7220316)

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPS15 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EPS15 anticorps

Épitope: pTyr849

Fonction: Rabbit Anti-Eps15 (phospho Tyr849) Polyclonal Antibody

Specificité: Phospho-Eps15 (Y849) Polyclonal Antibody detects endogenous levels of Eps15 protein only when phosphorylated at Y849.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Eps15 Phospho-Tyr849

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur EPS15

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Autre désignation: Eps15

Sujet: EPS15, AF1P, Epidermal growth factor receptor substrate 15, Protein Eps15, Protein AF-1pEPS15 encodes epidermal growth factor receptor pathway substrate 15 that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, EPS15 is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 100kD

ID gène: 2060

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation