ERD21 anticorps

N° du produit ABIN7228428

L’anticorps anti-ERD21 Polyclonal Lapin est utilisé pour la détection de ERD21 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA et WB.

Aperçu rapide pour ERD21 anticorps (ABIN7228428)

Antigène: ERD21 (LOC108903962) (ER Lumen Protein-Retaining Receptor 1-Like (LOC108903962))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERD21 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-ERD21 anticorps

Fonction: Rabbit Anti-ERD21 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ERD21 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ERD21 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ERD21

Antigène: ERD21 (LOC108903962) (ER Lumen Protein-Retaining Receptor 1-Like (LOC108903962))

Autre désignation: ERD21

Sujet: ER lumen protein-retaining receptor 1, KDEL endoplasmic reticulum protein retention receptor 1, KDEL receptor 1, Putative MAPK-activating protein PM23Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.

Poids moléculaire: 23kD

ID gène: 10945

UniProt: P24390