ERLIN1/2 anticorps (AA 31-80)

N° du produit ABIN7226896

L’anticorps anti-ERLIN1/2 Polyclonal Lapin est utilisé pour la détection de ERLIN1/2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA et WB.

Aperçu rapide pour ERLIN1/2 anticorps (AA 31-80) (ABIN7226896)

Antigène: ERLIN1/2

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERLIN1/2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-ERLIN1/2 anticorps

Épitope: AA 31-80

Fonction: Rabbit Anti-ERLIN1/2 Polyclonal Antibody

Specificité: ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from ERLIN1/2 at AA range: 31-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ERLIN1/2

Antigène: ERLIN1/2

Sujet: Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation.

Poids moléculaire: 40kD,42kD

UniProt: O75477, O94905