ETV1 anticorps (AA 10-90)

N° du produit ABIN7214790

Cet anticorps Lapin Polyclonal détecte spécifiquement ETV1 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ETV1 anticorps (AA 10-90) (ABIN7214790)

Antigène: ETV1 (Ets Variant 1 (ETV1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ETV1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ETV1 anticorps

Épitope: AA 10-90

Fonction: ER81 Polyclonal Antibody

Specificité: ER81 Polyclonal Antibody detects endogenous levels of ER81 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human ER81 at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ETV1

Antigène: ETV1 (Ets Variant 1 (ETV1))

Autre désignation: ER81

Sujet: Rabbit Anti-ER81 Polyclonal Antibody,ETV1, ER81, ETS translocation variant 1, Ets-related protein 81,ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,ETS translocation variant 1

Poids moléculaire: observerd band 60kDa

ID gène: 2115

UniProt: P50549