Ezrin anticorps (pTyr146)
Aperçu rapide pour Ezrin anticorps (pTyr146) (ABIN7224916)
Antigène
Voir toutes Ezrin (EZR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr146
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Fonction
- Ezrin (phospho Tyr146) Polyclonal Antibody
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Specificité
- Phospho-Ezrin (Y146) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y146.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human Ezrin Phospho-Tyr146
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Ezrin (EZR)
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Autre désignation
- Ezrin
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Sujet
- Rabbit Anti-Ezrin (phospho Tyr146) Polyclonal Antibody,EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81,The cytoplasmic peripheral membrane protein encoded by EZR (ezrin) functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for EZR. Alternatively spliced variants have also been described for EZR.,Ezrin
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Poids moléculaire
- observerd band 69kDa
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ID gène
- 7430
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UniProt
- P15311
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Pathways
- Maintenance of Protein Location
Antigène
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