Ezrin anticorps (pTyr478)

N° du produit ABIN7224918

Cet anticorps Lapin Polyclonal détecte spécifiquement Ezrin dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Ezrin anticorps (pTyr478) (ABIN7224918)

Antigène: Ezrin (EZR)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ezrin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Ezrin anticorps

Épitope: pTyr478

Fonction: Rabbit Anti-Ezrin (phospho Tyr478) Polyclonal Antibody

Specificité: Phospho-Ezrin (Y478) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y478.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Ezrin Phospho-Tyr478

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Ezrin

Antigène: Ezrin (EZR)

Autre désignation: Ezrin

Sujet: EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81The cytoplasmic peripheral membrane protein encoded by EZR (ezrin) functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for EZR. Alternatively spliced variants have also been described for EZR.

Poids moléculaire: 70kD

ID gène: 7430

UniProt: P15311

Pathways: Maintenance of Protein Location