F11R anticorps (Internal Region)
Aperçu rapide pour F11R anticorps (Internal Region) (ABIN7218478)
Antigène
Voir toutes F11R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Fonction
- JAM-A Polyclonal Antibody
-
Specificité
- JAM-A Polyclonal Antibody detects endogenous levels of JAM-A protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from the Internal region of human JAM-A
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- F11R (F11 Receptor (F11R))
-
Autre désignation
- JAM-A
-
Sujet
- Rabbit Anti-JAM-A Polyclonal Antibody,F11R, JAM1, JCAM, Junctional adhesion molecule A, JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, PAM-1, CD321,Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. F11 receptor encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.,Junctional adhesion molecule A
-
Poids moléculaire
- observerd band 32kDa
-
ID gène
- 50848
-
UniProt
- Q9Y624
-
Pathways
- Cell-Cell Junction Organization
Antigène
-