FAM111B anticorps (AA 250-330)

N° du produit ABIN7221972

Cet anticorps Lapin Polyclonal détecte spécifiquement FAM111B dans ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FAM111B anticorps (AA 250-330) (ABIN7221972)

Antigène: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM111B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FAM111B anticorps

Épitope: AA 250-330

Fonction: Rabbit Anti-FAM111B Polyclonal Antibody

Specificité: FAM111B Polyclonal Antibody detects endogenous levels of FAM111B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human FAM111B at AA range: 250-330

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:200,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FAM111B

Antigène: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Autre désignation: FAM111B

Sujet: FAM111B, CANP, Protein FAM111B, Cancer-associated nucleoproteinFAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.

ID gène: 374393

UniProt: Q6SJ93