FAM3D anticorps (AA 121-170)

N° du produit ABIN7226874

L’anticorps anti-FAM3D Polyclonal Lapin est utilisé pour la détection de FAM3D dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour FAM3D anticorps (AA 121-170) (ABIN7226874)

Antigène: FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM3D est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FAM3D anticorps

Épitope: AA 121-170

Fonction: Rabbit Anti-FAM3D Polyclonal Antibody

Specificité: FAM3D Polyclonal Antibody detects endogenous levels of FAM3D.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from FAM3D at AA range: 121-170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FAM3D

Antigène: FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))

Autre désignation: FAM3D

Sujet: Protein FAM3DFamily with sequence similarity 3 (FAM3) family is a novel cytokine-like gene family, which has four genes in this family, FAM3A, FAM3B, FAM3C, and FAM3D, each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. It had indicated that FAM3B/PANDER (pancreatic derived factor) is highly expressed in pancreas, and FAM3A and FAM3C in almost all tissues. FAM3D is abundantly expressed in placenta and weakly expressed in small intestine. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium, particularly capillaries. FAM3A and FAM3B protein were both localized to the islets of Langerhans of the endocrine pancreas. Recombinant FAM3B protein has delayed effects on beta-cell function. FAM3C is involved in retinal laminar formation processes in vertebrates. NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy. Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS), CNS hypersonia similar to narcolepsy.

Poids moléculaire: 22kD

ID gène: 131177

UniProt: Q96BQ1