FAT1 anticorps (AA 1140-1220)

N° du produit ABIN7228488

Cet anticorps Lapin Polyclonal détecte spécifiquement FAT1 dans IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FAT1 anticorps (AA 1140-1220) (ABIN7228488)

Antigène: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAT1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FAT1 anticorps

Épitope: AA 1140-1220

Fonction: Rabbit Anti-FAT1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of FAT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human FAT1 protein at AA range: 1140-1220

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FAT1

Antigène: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Autre désignation: FAT1

Sujet: Protocadherin Fat 1, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog, Protocadherin Fat 1, nuclear formFAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Poids moléculaire: 504kD

ID gène: 2195

UniProt: Q14517