FARP2 anticorps (AA 300-380)

N° du produit ABIN7214904

Cet anticorps anti-FARP2 Polyclonal Lapin (ABIN7214904) détecte spécifiquement FARP2 dans ELISA, WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour FARP2 anticorps (AA 300-380) (ABIN7214904)

Antigène: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FARP2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-FARP2 anticorps

Épitope: AA 300-380

Fonction: Rabbit Anti-FIR Polyclonal Antibody

Specificité: FIR Polyclonal Antibody detects endogenous levels of FIR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human FIR at AA range: 300-380

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FARP2

Antigène: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Autre désignation: FIR

Sujet: FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3FARP2 is a Protein Coding gene. FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion. Diseases associated with FARP2 include verheij syndrome and aarskog-scott syndrome. Among its related pathways are Developmental Biology and Adherens junction. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac guanyl-nucleotide exchange factor activity. An important paralog of this gene is FRMD3.

Poids moléculaire: 119kD

ID gène: 9855

UniProt: O94887