FIL1L anticorps (AA 30-110)

N° du produit ABIN7214602

L’anticorps anti-FIL1L Polyclonal Lapin est utilisé pour la détection de FIL1L dans des échantillons de Humain et Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour FIL1L anticorps (AA 30-110) (ABIN7214602)

Antigène: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIL1L est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-FIL1L anticorps

Épitope: AA 30-110

Fonction: Rabbit Anti-DOC-1 Polyclonal Antibody

Specificité: DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human DOC-1 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FIL1L

Antigène: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Autre désignation: DOC-1

Sujet: CDK2AP1, CDKAP1, DOC1, Cyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressorCyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 20kD

ID gène: 8099

UniProt: O14519