Flk-1/Flt-4 (pTyr1054) anticorps

N° du produit ABIN7222030

L’anticorps anti-Flk-1/Flt-4 Polyclonal Lapin est utilisé pour la détection de Flk-1/Flt-4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour Flk-1/Flt-4 (pTyr1054) anticorps (ABIN7222030)

Antigène: Flk-1/Flt-4

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit

Épitope: pTyr1054

Fonction: Rabbit Anti-Flk-1/Flt-4 (phospho Tyr1054/Y1063) Polyclonal Antibody

Specificité: Phospho-Flk-1/Flt-4 (Y1054/Y1063) Polyclonal Antibody detects endogenous levels of Flk-1/Flt-4 protein only when phosphorylated at Y1054/Y1063.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Flk-1/Flt-4 Phospho-Tyr1054/Y1063

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Flk-1/Flt-4

Sujet: KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD antigen CD309, FLT4, VEGFR3, Vascular endothelial growthVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt-1, KDR/Flk-1, Flt-4, tie-1, and tek/tie-2) whose expression is almost exclusively restricted to the endothelial cells. Tie-1 and tek/tie-2 define a new class of RTKs containing two immunoglobulin-like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt-1, KDR/Flk-1 and Flt-4 are members of the class III subfamily of RTKs containing seven immunoglobulin-like repeats in their extracellular domains. All five RTKs are likely to play central roles in vasculogenesis and angiogenesis.

ID gène: 3791, 2324

UniProt: P35968, P35916