FPR2 anticorps (AA 130-210)

N° du produit ABIN7228588

L’anticorps anti-FPR2 Polyclonal Lapin est utilisé pour la détection de FPR2 dans des échantillons de Humain, Souris, Rat et Porc. Il a été validé pour WB et ELISA.

Aperçu rapide pour FPR2 anticorps (AA 130-210) (ABIN7228588)

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FPR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FPR2 anticorps

Épitope: AA 130-210

Fonction: Rabbit Anti-FPR2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of FPR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human FPR2 protein at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FPR2

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Autre désignation: FPR2

Sujet: N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFPFPR2 (Formyl Peptide Receptor 2) is a Protein Coding gene. Diseases associated with FPR2 include Prion Disease. Among its related pathways are Akt Signaling and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and N-formyl peptide receptor activity. An important paralog of this gene is FPR3. Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Poids moléculaire: 38kD

ID gène: 2358

UniProt: P25090