FRAT1 anticorps (AA 130-210)
Aperçu rapide pour FRAT1 anticorps (AA 130-210) (ABIN7228590)
Antigène
Voir toutes FRAT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 130-210
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Fonction
- Rabbit Anti-FRAT1 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of FRAT1 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human FRAT1 protein at AA range: 130-210
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
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Autre désignation
- FRAT1
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Sujet
- Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1FRAT1 (FRAT1, WNT Signaling Pathway Regulator) is a Protein Coding gene. Among its related pathways are Endometrial cancer and Signaling by Wnt. An important paralog of this gene is FRAT2. The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
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Poids moléculaire
- 30kD
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ID gène
- 10023
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UniProt
- Q92837
Antigène
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