GPS2 anticorps (AA 30-110)

N° du produit ABIN7221282

Cet anticorps anti-GPS2 Polyclonal Lapin (ABIN7221282) détecte spécifiquement GPS2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GPS2 anticorps (AA 30-110) (ABIN7221282)

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GPS2 anticorps

Épitope: AA 30-110

Fonction: Rabbit Anti-GPS2 Polyclonal Antibody

Specificité: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human GPS2 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GPS2

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Autre désignation: GPS2

Sujet: GPS2, G protein pathway suppressor 2, GPS-2GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Poids moléculaire: 40kD

ID gène: 2874

UniProt: Q13227