GPR172A anticorps (AA 20-100)

N° du produit ABIN7225074

Cet anticorps Lapin Polyclonal détecte spécifiquement GPR172A dans ELISA, WB et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GPR172A anticorps (AA 20-100) (ABIN7225074)

Antigène: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR172A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-GPR172A anticorps

Épitope: AA 20-100

Fonction: Rabbit Anti-GPR172A Polyclonal Antibody

Specificité: GPR172A Polyclonal Antibody detects endogenous levels of GPR172A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human GPR172A at AA range: 20-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GPR172A

Antigène: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Autre désignation: GPR172A

Sujet: SLC52A2, GPR172A, PAR1, RFT3, Solute carrier family 52, riboflavin transporter, member 2, Porcine endogenous retrovirus A receptor 1, PERV-A receptor 1, Protein GPR172A, Riboflavin transporter 3, hRFT3SLC52A2 (solute carrier family 52 member 2) encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, SLC52A2 has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in SLC52A2 have been associated with Brown-Vialetto-Van Laere syndrome 2--an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.

Poids moléculaire: 46kD

ID gène: 79581

UniProt: Q9HAB3

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response