GPR31 anticorps (AA 150-230)
Aperçu rapide pour GPR31 anticorps (AA 150-230) (ABIN7221238)
Antigène
Voir toutes GPR31 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 150-230
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Fonction
- GPR31 Polyclonal Antibody
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Specificité
- GPR31 Polyclonal Antibody detects endogenous levels of GPR31 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human GPR31 at AA range: 150-230
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GPR31 (G Protein-Coupled Receptor 31 (GPR31))
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Autre désignation
- GPR31
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Sujet
- Rabbit Anti-GPR31 Polyclonal Antibody,GPR31, 12-(S)-hydroxy-5, 8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, 12-HETER, G-protein coupled receptor 31,GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR3. igh-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.,12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor
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Poids moléculaire
- observerd band 33kDa
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ID gène
- 2853
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UniProt
- O00270
Antigène
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