GPR31 anticorps (AA 150-230)

N° du produit ABIN7221238

Cet anticorps Lapin Polyclonal détecte spécifiquement GPR31 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour GPR31 anticorps (AA 150-230) (ABIN7221238)

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR31 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GPR31 anticorps

Épitope: AA 150-230

Fonction: Rabbit Anti-GPR31 Polyclonal Antibody

Specificité: GPR31 Polyclonal Antibody detects endogenous levels of GPR31 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human GPR31 at AA range: 150-230

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GPR31

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Autre désignation: GPR31

Sujet: GPR31, 12-(S)-hydroxy-5, 8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, 12-HETER, G-protein coupled receptor 31GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR3. igh-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Poids moléculaire: 33kD

ID gène: 2853

UniProt: O00270