GABARAP anticorps

N° du produit ABIN7226848

L’anticorps anti-GABARAP Polyclonal Lapin est utilisé pour la détection de GABARAP dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour GABARAP anticorps (ABIN7226848)

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABARAP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GABARAP anticorps

Fonction: Rabbit Anti-GABARAP Polyclonal Antibody

Specificité: GABARAP Polyclonal Antibody detects endogenous levels of GABARAP.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic Peptide of GABARAP

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GABARAP

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Autre désignation: GABARAP

Sujet: GABA(A) receptor-associated protein-like 2GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa, GATE-16) was originally characterized as a factor essential for intra-Golgi protein transport. Later GABARAPL2 along with LC3 and GABARAP, were identified as the homologs of yeast ATG8 which is a unique ubiquitin-like protein essential for autophagy. When induced GABARAPL2 is first digested by ATG4 family enzymes to become its mature form: gABARAPL2-I, later conjugated to PE lipid as lipidated form: gABARAPL2-II. The lipidated form migrates faster than its mature form on SDS-PAGE gel. GABARAPL2 is strongly expressed in the brain. This antibody is specific to GABARAPL2. It has no cross-reaction to other GABARAP protein.

Poids moléculaire: 17kD

ID gène: 11345

UniProt: P60520

Pathways: Autophagy